7CE3
Crystal structure of human IDH3 holoenzyme in APO form.
Summary for 7CE3
Entry DOI | 10.2210/pdb7ce3/pdb |
Descriptor | Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial, Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial (3 entities in total) |
Functional Keywords | idh3, nad-idh, nad dependent isocitrate dehydrogenase, oxidoreductase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 158399.11 |
Authors | Sun, P.K.,Ding, J.P. (deposition date: 2020-06-21, release date: 2021-01-06, Last modification date: 2023-11-29) |
Primary citation | Sun, P.,Liu, Y.,Ma, T.,Ding, J. Structure and allosteric regulation of human NAD-dependent isocitrate dehydrogenase. Cell Discov, 6:94-94, 2020 Cited by PubMed: 33349631DOI: 10.1038/s41421-020-00220-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.472 Å) |
Structure validation
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