7CCX
Crystal structure of the holo form of human hydroxymethylbilane synthase
Summary for 7CCX
Entry DOI | 10.2210/pdb7ccx/pdb |
Descriptor | Porphobilinogen deaminase, 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid (3 entities in total) |
Functional Keywords | porphyrin synthesis, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 79606.85 |
Authors | Sato, H.,Sugishima, M.,Wada, K.,Hirabayashi, K.,Tsukaguchi, M. (deposition date: 2020-06-18, release date: 2021-03-17, Last modification date: 2023-11-29) |
Primary citation | Sato, H.,Sugishima, M.,Tsukaguchi, M.,Masuko, T.,Iijima, M.,Takano, M.,Omata, Y.,Hirabayashi, K.,Wada, K.,Hisaeda, Y.,Yamamoto, K. Crystal structures of hydroxymethylbilane synthase complexed with a substrate analog: a single substrate-binding site for four consecutive condensation steps. Biochem.J., 478:1023-1042, 2021 Cited by PubMed: 33600566DOI: 10.1042/BCJ20200996 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.84 Å) |
Structure validation
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