7CCS
Consensus mutated xCT-CD98hc complex
Summary for 7CCS
Entry DOI | 10.2210/pdb7ccs/pdb |
EMDB information | 30341 |
Descriptor | 4F2 cell-surface antigen heavy chain, Consensus mutated Anionic Amino Acid Transporter Light Chain, Xc- System (2 entities in total) |
Functional Keywords | transporter, membrane protein, complex, transport protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 124003.48 |
Authors | Oda, K.,Lee, Y.,Takemoto, M.,Yamashita, K.,Nishizawa, T.,Nureki, O. (deposition date: 2020-06-17, release date: 2020-12-09, Last modification date: 2020-12-16) |
Primary citation | Oda, K.,Lee, Y.,Wiriyasermkul, P.,Tanaka, Y.,Takemoto, M.,Yamashita, K.,Nagamori, S.,Nishizawa, T.,Nureki, O. Consensus mutagenesis approach improves the thermal stability of system x c - transporter, xCT, and enables cryo-EM analyses. Protein Sci., 29:2398-2407, 2020 Cited by PubMed: 33016372DOI: 10.1002/pro.3966 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (6.2 Å) |
Structure validation
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