7CA3
Cryo-EM structure of human GABA(B) receptor bound to the positive allosteric modulator rac-BHFF
Summary for 7CA3
Entry DOI | 10.2210/pdb7ca3/pdb |
EMDB information | 30323 |
Descriptor | Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, CHOLESTEROL, ... (4 entities in total) |
Functional Keywords | gpcr, gaba, neurosignalling, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 180969.76 |
Authors | |
Primary citation | Kim, Y.,Jeong, E.,Jeong, J.H.,Kim, Y.,Cho, Y. Structural Basis for Activation of the Heterodimeric GABA B Receptor. J.Mol.Biol., 432:5966-5984, 2020 Cited by PubMed: 33058878DOI: 10.1016/j.jmb.2020.09.023 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.5 Å) |
Structure validation
Download full validation report