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7C2E

GLP-1R-Gs complex structure with a small molecule full agonist

Summary for 7C2E
Entry DOI10.2210/pdb7c2e/pdb
EMDB information30274
DescriptorGuanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
Functional Keywordsgpcr, cryoem, glp-1, membrane protein
Biological sourceHomo sapiens
More
Total number of polymer chains5
Total formula weight164522.37
Authors
Ma, H.,Yuan, D.P.,Huang, W.,Wenge, Z.,Xu, E. (deposition date: 2020-05-07, release date: 2020-08-26, Last modification date: 2020-12-16)
Primary citationMa, H.,Huang, W.,Wang, X.,Zhao, L.,Jiang, Y.,Liu, F.,Guo, W.,Sun, X.,Zhong, W.,Yuan, D.,Xu, H.E.
Structural insights into the activation of GLP-1R by a small molecule agonist.
Cell Res., 30:1140-1142, 2020
Cited by
PubMed: 32724086
DOI: 10.1038/s41422-020-0384-8
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (4.2 Å)
Structure validation

227111

数据于2024-11-06公开中

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