7C1S

Crystal structure of the starter condensation domain of rhizomide synthetase RzmA mutant H140A/R148A in complex with C8-CoA and Leu-SNAC

Summary for 7C1S

Entry DOI	10.2210/pdb7c1s/pdb
Related	7C1H 7C1K 7C1L 7C1P 7C1R
Descriptor	Non-ribosomal peptide synthetase modules, OCTANOYL-COENZYME A, S-(2-acetamidoethyl) (2S)-2-azanyl-4-methyl-pentanethioate, ... (4 entities in total)
Functional Keywords	nonribosomal peptide synthesis, rzma-cs, starter condensation (cs) domains, c8-coa, leu-snac, biosynthetic protein
Biological source	Paraburkholderia rhizoxinica HKI 454
Total number of polymer chains	1
Total formula weight	49544.86
Authors	Zhong, L.,Diao, X.,Zhang, N.,Li, F.W.,Zhou, H.B.,Chen, H.N.,Ren, X.,Zhang, Y.,Wu, D.,Bian, X. (deposition date: 2020-05-05, release date: 2020-11-25, Last modification date: 2023-11-29)
Primary citation	Zhong, L.,Diao, X.,Zhang, N.,Li, F.,Zhou, H.,Chen, H.,Bai, X.,Ren, X.,Zhang, Y.,Wu, D.,Bian, X. Engineering and elucidation of the lipoinitiation process in nonribosomal peptide biosynthesis. Nat Commun, 12:296-296, 2021 Cited by PubMed: 33436600 DOI: 10.1038/s41467-020-20548-8 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.586 Å)

Structure validation