7C06
Crystal structure of yeast U2AF1 complex bound to 3' splice site RNA, 5'-UAGGU.
Summary for 7C06
Entry DOI | 10.2210/pdb7c06/pdb |
Descriptor | Splicing factor U2AF 23 kDa subunit, Splicing factor U2AF 59 kDa subunit, RNA (5'-R(*U*UP*AP*GP*GP*U)-3'), ... (4 entities in total) |
Functional Keywords | pre-mrna, splicing, intron, 3' splice site, zinc-finger, splicing-rna complex, splicing/rna |
Biological source | Schizosaccharomyces pombe 972h- (Fission yeast) More |
Total number of polymer chains | 27 |
Total formula weight | 314271.93 |
Authors | Yoshida, H.,Park, S.Y.,Urano, T.,Obayashi, E. (deposition date: 2020-04-30, release date: 2020-09-30, Last modification date: 2023-11-29) |
Primary citation | Yoshida, H.,Park, S.Y.,Sakashita, G.,Nariai, Y.,Kuwasako, K.,Muto, Y.,Urano, T.,Obayashi, E. Elucidation of the aberrant 3' splice site selection by cancer-associated mutations on the U2AF1. Nat Commun, 11:4744-4744, 2020 Cited by PubMed: 32958768DOI: 10.1038/s41467-020-18559-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.02 Å) |
Structure validation
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