7BZ2

Cryo-EM structure of the formoterol-bound beta2 adrenergic receptor-Gs protein complex.

7BZ2 の概要

• エントリーDOI: 10.2210/pdb7bz2/pdb
• EMDBエントリー: 30249
• 分子名称: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• 機能のキーワード: receptor, formoterol, complex, signaling protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 151803.50

構造登録者

Zhang, Y.N.,Yang, F.,Ling, S.L.,Lv, P.,Zhou, Y.X.,Fang, W.,Sun, W.,Shi, P.,Tian, C.L. (登録日: 2020-04-26, 公開日: 2020-08-05)

• 主引用文献: Zhang, Y.,Yang, F.,Ling, S.,Lv, P.,Zhou, Y.,Fang, W.,Sun, W.,Zhang, L.,Shi, P.,Tian, C.; Single-particle cryo-EM structural studies of the beta2AR-Gs complex bound with a full agonist formoterol.; Cell Discov, 6:45-45, 2020; PubMed: 32655881; DOI: 10.1038/s41421-020-0176-9

実験手法

ELECTRON MICROSCOPY (3.82 Å)