7BYM
Cryo-EM structure of human KCNQ4 with retigabine
Summary for 7BYM
Entry DOI | 10.2210/pdb7bym/pdb |
EMDB information | 30245 |
Descriptor | Green fluorescent protein,Potassium voltage-gated channel subfamily KQT member 4, Calmodulin-3, [(2R)-1-octadecanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8Z)-icosa-5,8,11,14-tetraenoate, ... (6 entities in total) |
Functional Keywords | kcnq, channel, calmodulin, pip2, retigabine, membrane protein |
Biological source | Aequorea victoria (Jellyfish) More |
Total number of polymer chains | 8 |
Total formula weight | 510240.49 |
Authors | |
Primary citation | Li, T.,Wu, K.,Yue, Z.,Wang, Y.,Zhang, F.,Shen, H. Structural Basis for the Modulation of Human KCNQ4 by Small-Molecule Drugs. Mol.Cell, 81:25-, 2021 Cited by PubMed: 33238160DOI: 10.1016/j.molcel.2020.10.037 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.1 Å) |
Structure validation
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