7BVH
Crystal structure of arabinosyltransferase EmbC2-AcpM2 complex from Mycobacterium smegmatis complexed with di-arabinose
Summary for 7BVH
Entry DOI | 10.2210/pdb7bvh/pdb |
Related PRD ID | PRD_900018 |
Descriptor | Integral membrane indolylacetylinositol arabinosyltransferase EmbC, Meromycolate extension acyl carrier protein, alpha-D-arabinofuranose-(1-5)-alpha-D-arabinofuranose, ... (7 entities in total) |
Functional Keywords | cell wall synthesis, arabinosyltransferase, drug target, transferase |
Biological source | Mycolicibacterium smegmatis MC2 155 More |
Total number of polymer chains | 4 |
Total formula weight | 264975.47 |
Authors | |
Primary citation | Zhang, L.,Zhao, Y.,Gao, Y.,Wu, L.,Gao, R.,Zhang, Q.,Wang, Y.,Wu, C.,Wu, F.,Gurcha, S.S.,Veerapen, N.,Batt, S.M.,Zhao, W.,Qin, L.,Yang, X.,Wang, M.,Zhu, Y.,Zhang, B.,Bi, L.,Zhang, X.,Yang, H.,Guddat, L.W.,Xu, W.,Wang, Q.,Li, J.,Besra, G.S.,Rao, Z. Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol. Science, 368:1211-1219, 2020 Cited by PubMed: 32327601DOI: 10.1126/science.aba9102 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.3 Å) |
Structure validation
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