7BV2
The nsp12-nsp7-nsp8 complex bound to the template-primer RNA and triphosphate form of Remdesivir(RTP)
Summary for 7BV2
Entry DOI | 10.2210/pdb7bv2/pdb |
EMDB information | 30210 |
Descriptor | RNA-directed RNA polymerase, Non-structural protein 8, Non-structural protein 7, ... (10 entities in total) |
Functional Keywords | sars-cov-2, rna polymerase, remdesivir, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More |
Total number of polymer chains | 5 |
Total formula weight | 159190.94 |
Authors | |
Primary citation | Yin, W.,Mao, C.,Luan, X.,Shen, D.D.,Shen, Q.,Su, H.,Wang, X.,Zhou, F.,Zhao, W.,Gao, M.,Chang, S.,Xie, Y.C.,Tian, G.,Jiang, H.W.,Tao, S.C.,Shen, J.,Jiang, Y.,Jiang, H.,Xu, Y.,Zhang, S.,Zhang, Y.,Xu, H.E. Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir. Science, 368:1499-1504, 2020 Cited by PubMed: 32358203DOI: 10.1126/science.abc1560 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.5 Å) |
Structure validation
Download full validation report