7BUQ
mcGAS bound with 23-cGAMP
Summary for 7BUQ
Entry DOI | 10.2210/pdb7buq/pdb |
Related | 7BUJ |
Descriptor | Cyclic GMP-AMP synthase, ZINC ION, cGAMP, ... (4 entities in total) |
Functional Keywords | mcgas, activator, inverted-orientation, metal-ion binding protein, immune system |
Biological source | Mus musculus (Mouse) |
Total number of polymer chains | 2 |
Total formula weight | 118079.37 |
Authors | |
Primary citation | Zhao, Z.,Ma, Z.,Wang, B.,Guan, Y.,Su, X.D.,Jiang, Z. Mn2+Directly Activates cGAS and Structural Analysis Suggests Mn2+Induces a Noncanonical Catalytic Synthesis of 2'3'-cGAMP. Cell Rep, 32:108053-108053, 2020 Cited by PubMed: 32814054DOI: 10.1016/j.celrep.2020.108053 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.091 Å) |
Structure validation
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