7BTA

Crystal structure of Rheb D60K mutant bound to GDP

Summary for 7BTA

• Entry DOI: 10.2210/pdb7bta/pdb
• Descriptor: GTP-binding protein Rheb, GUANOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, ... (4 entities in total)
• Functional Keywords: mtorc1, small gtpase, rheb, signaling protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 41402.46

Authors

Zhang, C.,Zhang, T.,Ding, J. (deposition date: 2020-03-31, release date: 2020-06-17, Last modification date: 2023-11-29)

• Primary citation: Zhang, C.,Liu, Y.,Zhang, Y.,Wang, X.,Zhang, T.,Ding, J.; Molecular basis for the functions of dominantly active Y35N and inactive D60K Rheb mutants in mTORC1 signaling.; J Mol Cell Biol, 12:741-744, 2020; PubMed: 32470140; DOI: 10.1093/jmcb/mjaa025

Experimental method

X-RAY DIFFRACTION (2.6 Å)