Summary for 7D1M
| Entry DOI | 10.2210/pdb7d1m/pdb |
| Descriptor | 3C-like proteinase, (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, DIMETHYL SULFOXIDE, ... (4 entities in total) |
| Functional Keywords | sars-cov-2, main protease, inhibitor, gc376, viral protein |
| Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) |
| Total number of polymer chains | 2 |
| Total formula weight | 68814.43 |
| Authors | Fu, L.F.,Gilski, M.,Shabalin, I.,Gao, G.F.,Qi, J.X. (deposition date: 2020-09-14, release date: 2020-10-28, Last modification date: 2023-11-29) |
| Primary citation | Fu, L.,Ye, F.,Feng, Y.,Yu, F.,Wang, Q.,Wu, Y.,Zhao, C.,Sun, H.,Huang, B.,Niu, P.,Song, H.,Shi, Y.,Li, X.,Tan, W.,Qi, J.,Gao, G.F. Both Boceprevir and GC376 efficaciously inhibit SARS-CoV-2 by targeting its main protease. Nat Commun, 11:4417-4417, 2020 Cited by PubMed: 32887884DOI: 10.1038/s41467-020-18233-x PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.35 Å) |
Structure validation
Download full validation report
