7BR2

BT4096 a gut microbial diltiazem-metabolizing enzyme

Summary for 7BR2

• Entry DOI: 10.2210/pdb7br2/pdb
• Descriptor: Lipolytic enzyme, G-D-S-L family (2 entities in total)
• Functional Keywords: gut microbe, diltiazem, drug metabolism, sgnh, gdsl, serine esterase, hydrolase
• Biological source: Bacteroides thetaiotaomicron
• Total number of polymer chains: 4
• Total formula weight: 206859.41

Authors

Ko, T.-P.,Chen, C.-C.,Guo, R.-T. (deposition date: 2020-03-26, release date: 2020-05-06, Last modification date: 2024-03-27)

• Primary citation: Zhou, S.,Ko, T.P.,Huang, J.W.,Liu, W.,Zheng, Y.,Wu, S.,Wang, Q.,Xie, Z.,Liu, Z.,Chen, C.C.,Guo, R.T.; Structure of a gut microbial diltiazem-metabolizing enzyme suggests possible substrate binding mode.; Biochem.Biophys.Res.Commun., 527:799-804, 2020; PubMed: 32423809; DOI: 10.1016/j.bbrc.2020.04.116

Experimental method

X-RAY DIFFRACTION (2.33 Å)