7BR2
BT4096 a gut microbial diltiazem-metabolizing enzyme
Summary for 7BR2
Entry DOI | 10.2210/pdb7br2/pdb |
Descriptor | Lipolytic enzyme, G-D-S-L family (2 entities in total) |
Functional Keywords | gut microbe, diltiazem, drug metabolism, sgnh, gdsl, serine esterase, hydrolase |
Biological source | Bacteroides thetaiotaomicron |
Total number of polymer chains | 4 |
Total formula weight | 206859.41 |
Authors | Ko, T.-P.,Chen, C.-C.,Guo, R.-T. (deposition date: 2020-03-26, release date: 2020-05-06, Last modification date: 2024-03-27) |
Primary citation | Zhou, S.,Ko, T.P.,Huang, J.W.,Liu, W.,Zheng, Y.,Wu, S.,Wang, Q.,Xie, Z.,Liu, Z.,Chen, C.C.,Guo, R.T. Structure of a gut microbial diltiazem-metabolizing enzyme suggests possible substrate binding mode. Biochem.Biophys.Res.Commun., 527:799-804, 2020 Cited by PubMed: 32423809DOI: 10.1016/j.bbrc.2020.04.116 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.33 Å) |
Structure validation
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