7BO3

Human Butyrylcholinesterase in complex with N-(2-(1H-Indol-3-yl)ethyl)-2-cycloheptyl-N-methylethan-1-amine

Summary for 7BO3

Entry DOI	10.2210/pdb7bo3/pdb
Descriptor	Cholinesterase, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
Functional Keywords	butyrylcholinesterase, complex, inhibitor, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	63053.79
Authors	Brazzolotto, X.,Meden, A.,Knez, D.,Nachon, F.,Gobec, S. (deposition date: 2021-01-23, release date: 2022-03-02, Last modification date: 2024-01-31)
Primary citation	Meden, A.,Knez, D.,Brazzolotto, X.,Nachon, F.,Dias, J.,Svete, J.,Stojan, J.,Groselj, U.,Gobec, S. From tryptophan-based amides to tertiary amines: Optimization of a butyrylcholinesterase inhibitor series. Eur.J.Med.Chem., 234:114248-114248, 2022 Cited by PubMed: 35299116 DOI: 10.1016/j.ejmech.2022.114248 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation