7BLB

BAZ2A bromodomain in complex with GSK4027 chemical probe

Summary for 7BLB

• Entry DOI: 10.2210/pdb7blb/pdb
• Related: 5MLJ 7BL8 7BL9 7BLA 7K6R
• Descriptor: Bromodomain adjacent to zinc finger domain protein 2A, 4-bromo-2-methyl-5-[[(3~{R},5~{R})-1-methyl-5-phenyl-piperidin-3-yl]amino]pyridazin-3-one (3 entities in total)
• Functional Keywords: four helical bundle, transcription
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 12741.15

Authors

Dalle Vedove, A.,Cazzanelli, G.,Caflisch, A.,Lolli, G. (deposition date: 2021-01-18, release date: 2022-03-02, Last modification date: 2024-01-31)

• Primary citation: Cazzanelli, G.,Dalle Vedove, A.,D'Agostino, V.G.,Caflisch, A.,Lolli, G.; Chemical probes in the BAZ2A bromodomain; to be published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)