7BLA
BAZ2A bromodomain in complex with TP-238 chemical probe
Summary for 7BLA
Entry DOI | 10.2210/pdb7bla/pdb |
Related | 7BL8 7BL9 7KDZ |
Descriptor | Bromodomain adjacent to zinc finger domain protein 2A, 6-{4-[3-(dimethylamino)propoxy]phenyl}-2-(methylsulfonyl)-N-[3-(1H-pyrazol-1-yl)propyl]pyrimidin-4-amine (3 entities in total) |
Functional Keywords | four helical bundle, transcription |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 12822.45 |
Authors | Dalle Vedove, A.,Cazzanelli, G.,Caflisch, A.,Lolli, G. (deposition date: 2021-01-18, release date: 2022-03-02, Last modification date: 2024-01-31) |
Primary citation | Cazzanelli, G.,Dalle Vedove, A.,D'Agostino, V.G.,Caflisch, A.,Lolli, G. Chemical probes in the BAZ2A bromodomain to be published, |
Experimental method | X-RAY DIFFRACTION (1.086 Å) |
Structure validation
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