7BFA
4-(2-(3-(4-iodophenyl)thioureido)ethyl)benzenesulfonamide in complex with Carbonic Anhydrase II
This is a non-PDB format compatible entry.
Summary for 7BFA
| Entry DOI | 10.2210/pdb7bfa/pdb |
| Descriptor | Carbonic anhydrase 2, ZINC ION, 1-(4-iodophenyl)-3-[2-(4-sulfamoylphenyl)ethyl]thiourea, ... (5 entities in total) |
| Functional Keywords | carbonic anhydrase ii, inhibitors, sulfonamide, lyase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 29907.91 |
| Authors | Angeli, A.,Ferraroni, M. (deposition date: 2021-01-02, release date: 2022-01-12, Last modification date: 2024-01-31) |
| Primary citation | Angeli, A.,Ferraroni, M.,Da'dara, A.A.,Selleri, S.,Pinteala, M.,Carta, F.,Skelly, P.J.,Supuran, C.T. Structural Insights into Schistosoma mansoni Carbonic Anhydrase (SmCA) Inhibition by Selenoureido-Substituted Benzenesulfonamides. J.Med.Chem., 64:10418-10428, 2021 Cited by PubMed: 34232641DOI: 10.1021/acs.jmedchem.1c00840 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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