7BE3

Human Galectin-3 in complex with LacdiNAc

Summary for 7BE3

• Entry DOI: 10.2210/pdb7be3/pdb
• Descriptor: Galectin-3, 2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, GLYCEROL, ... (5 entities in total)
• Functional Keywords: galectin-3, lacdinac, ldn, glycan, lectin, immune, sugar binding protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 16287.08

Authors

Trovao, F.,Carvalho, A.L. (deposition date: 2020-12-22, release date: 2021-04-21, Last modification date: 2024-01-31)

• Primary citation: Lima, C.D.L.,Coelho, H.,Gimeno, A.,Trovao, F.,Diniz, A.,Dias, J.S.,Jimenez-Barbero, J.,Corzana, F.,Carvalho, A.L.,Cabrita, E.J.,Marcelo, F.; Structural Insights into the Molecular Recognition Mechanism of the Cancer and Pathogenic Epitope, LacdiNAc by Immune-Related Lectins.; Chemistry, 27:7951-7958, 2021; PubMed: 33826192; DOI: 10.1002/chem.202100800

Experimental method

X-RAY DIFFRACTION (1.25 Å)