7BAI
Structure of RIG-I CTD (I875A) bound to p-RNA
Summary for 7BAI
Entry DOI | 10.2210/pdb7bai/pdb |
Descriptor | Antiviral innate immune response receptor RIG-I, RNA (5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3'), ZINC ION (3 entities in total) |
Functional Keywords | rna recognition, innate immunity, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 56479.76 |
Authors | Anand, K.,Hagelueken, G.,Fusshoeller, D.,Geyer, M. (deposition date: 2020-12-15, release date: 2022-01-12, Last modification date: 2024-01-31) |
Primary citation | de Regt, A.K.,Anand, K.,Gatterdam, K.,Hagelueken, G.,Hartmann, G.,Geyer, M.,Schlee, M. A conserved isoleucine in the RNA sensor RIG-I controls immune tolerance to mitochondrial RNA To Be Published, |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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