7BAG

C3b in complex with CP40

7BAG の概要

• エントリーDOI: 10.2210/pdb7bag/pdb
• 分子名称: Complement C3, Compstatin CP40, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: complement system, c3b, c3 convertase, inhibitor, immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 178330.76

構造登録者

Lamers, C.,Xue, X.,Smiesko, M.,van Son, H.,Wagner, B.,Sfyroera, G.,Gros, P.,Lambris, J.,Ricklin, D. (登録日: 2020-12-15, 公開日: 2022-01-12, 最終更新日: 2024-02-07)

• 主引用文献: Lamers, C.,Xue, X.,Smiesko, M.,van Son, H.,Wagner, B.,Berger, N.,Sfyroera, G.,Gros, P.,Lambris, J.D.,Ricklin, D.; Insight into mode-of-action and structural determinants of the compstatin family of clinical complement inhibitors.; Nat Commun, 13:5519-5519, 2022; PubMed: 36127336; DOI: 10.1038/s41467-022-33003-7

実験手法

X-RAY DIFFRACTION (2 Å)