7B73

Insight into the molecular determinants of thermal stability in halohydrin dehalogenase HheD2.

Summary for 7B73

Entry DOI	10.2210/pdb7b73/pdb
Descriptor	Short-chain dehydrogenase/reductase SDR, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, ... (4 entities in total)
Functional Keywords	thermostability, enantioselectivity changes, directed evolution, protein engineering, short-chain dehydrogenase/reductase enzyme superfamily, dehalogenase, lyase
Biological source	gamma proteobacterium HTCC2207
Total number of polymer chains	4
Total formula weight	105845.48
Authors	Wessel, J.,Petrillo, G.,Estevez, M.,Bosh, S.,Seeger, M.,Dijkman, W.P.,Hidalgo, A.,Uson, I.,Osuna, S.,Schallmey, A. (deposition date: 2020-12-09, release date: 2021-04-07, Last modification date: 2021-08-11)
Primary citation	Wessel, J.,Petrillo, G.,Estevez-Gay, M.,Bosch, S.,Seeger, M.,Dijkman, W.P.,Iglesias-Fernandez, J.,Hidalgo, A.,Uson, I.,Osuna, S.,Schallmey, A. Insights into the molecular determinants of thermal stability in halohydrin dehalogenase HheD2. Febs J., 288:4683-4701, 2021 Cited by PubMed: 33605544 DOI: 10.1111/febs.15777 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation