7B69

BK Polyomavirus VP1 pentamer core(residues 26-299) mutant C104S

This is a non-PDB format compatible entry.

Summary for 7B69

• Entry DOI: 10.2210/pdb7b69/pdb
• Descriptor: Major capsid protein VP1, DIMETHYL SULFOXIDE (3 entities in total)
• Functional Keywords: viral protein, polyomavirus, capsid protein
• Biological source: BK polyomavirus (BKPyV, Human polyomavirus 1)
• Total number of polymer chains: 10
• Total formula weight: 304097.72

Authors

Osipov, E.M.,Beelen, S.,Strelkov, S.V. (deposition date: 2020-12-07, release date: 2022-06-22, Last modification date: 2024-01-31)

• Primary citation: Osipov, E.M.,Munawar, A.H.,Beelen, S.,Fearon, D.,Douangamath, A.,Wild, C.,Weeks, S.D.,Van Aerschot, A.,von Delft, F.,Strelkov, S.V.; Discovery of novel druggable pockets on polyomavirus VP1 through crystallographic fragment-based screening to develop capsid assembly inhibitors.; Rsc Chem Biol, 3:1013-1027, 2022; PubMed: 35974998; DOI: 10.1039/d2cb00052k

Experimental method

X-RAY DIFFRACTION (1.474 Å)