7B2Z

Notum complex with ARUK3003907

Summary for 7B2Z

Entry DOI	10.2210/pdb7b2z/pdb
Descriptor	Palmitoleoyl-protein carboxylesterase NOTUM, SULFATE ION, DIMETHYL SULFOXIDE, ... (5 entities in total)
Functional Keywords	notum inhibitor, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	44619.30
Authors	Zhao, Y.,Jone, E.Y. (deposition date: 2020-11-28, release date: 2021-08-04, Last modification date: 2024-01-31)
Primary citation	Zhao, Y.,Svensson, F.,Steadman, D.,Frew, S.,Monaghan, A.,Bictash, M.,Moreira, T.,Chalk, R.,Lu, W.,Fish, P.V.,Jones, E.Y. Structural Insights into Notum Covalent Inhibition. J.Med.Chem., 64:11354-11363, 2021 Cited by PubMed: 34292747 DOI: 10.1021/acs.jmedchem.1c00701 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.24 Å)

Structure validation