7AW6

The extracellular region of CD33 with bound sialoside analogue P22

7AW6 の概要

• エントリーDOI: 10.2210/pdb7aw6/pdb
• 分子名称: Myeloid cell surface antigen CD33, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-aminoethyl 5-{[(4-cyclohexyl-1H-1,2,3-triazol-1-yl)acetyl]amino}-3,5,9-trideoxy-9-[(4-hydroxy-3,5-dimethylbenzene-1-carbonyl)amino]-D-glycero-alpha-D-galacto-non-2-ulopyranonosyl-(2->6)-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranoside, ... (6 entities in total)
• 機能のキーワード: receptor, siglec, ig-like, sialic acid, alzheimer's disease, lectin, cell surface antigen, immune system
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 59991.55

構造登録者

Bradshaw, W.J.,Katis, V.L.,Thompson, A.P.,Arrowsmith, C.H.,Edwards, A.M.,von Delft, F.,Bountra, C.,Gileadi, O. (登録日: 2020-11-06, 公開日: 2020-12-16, 最終更新日: 2024-01-31)

• 主引用文献: Bradshaw, W.J.,Katis, V.L.,Thompson, A.P.,Arrowsmith, C.H.,Edwards, A.M.,von Delft, F.,Bountra, C.,Gileadi, O.; The extracellular region of CD33 with bound sialoside analogue P22; To Be Published,

実験手法

X-RAY DIFFRACTION (1.95 Å)