7AUW
Inhibitory complex of human meprin beta with mouse fetuin-B.
Summary for 7AUW
| Entry DOI | 10.2210/pdb7auw/pdb |
| Descriptor | Meprin A subunit beta, alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, ... (15 entities in total) |
| Functional Keywords | protease inhibitor complex, zinc metallopeptidase, cystatin-type modules, hydrolase, hydrolase inhibitor |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 228924.81 |
| Authors | Eckhard, U.,Gomis-Ruth, F.X. (deposition date: 2020-11-03, release date: 2021-04-14, Last modification date: 2024-01-31) |
| Primary citation | Eckhard, U.,Korschgen, H.,von Wiegen, N.,Stocker, W.,Gomis-Ruth, F.X. The crystal structure of a 250-kDa heterotetrameric particle explains inhibition of sheddase meprin beta by endogenous fetuin-B. Proc.Natl.Acad.Sci.USA, 118:-, 2021 Cited by PubMed: 33782129DOI: 10.1073/pnas.2023839118 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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