7AUW

Inhibitory complex of human meprin beta with mouse fetuin-B.

7AUW の概要

• エントリーDOI: 10.2210/pdb7auw/pdb
• 分子名称: Meprin A subunit beta, alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, ... (15 entities in total)
• 機能のキーワード: protease inhibitor complex, zinc metallopeptidase, cystatin-type modules, hydrolase, hydrolase inhibitor
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 228924.81

構造登録者

Eckhard, U.,Gomis-Ruth, F.X. (登録日: 2020-11-03, 公開日: 2021-04-14, 最終更新日: 2024-01-31)

• 主引用文献: Eckhard, U.,Korschgen, H.,von Wiegen, N.,Stocker, W.,Gomis-Ruth, F.X.; The crystal structure of a 250-kDa heterotetrameric particle explains inhibition of sheddase meprin beta by endogenous fetuin-B.; Proc.Natl.Acad.Sci.USA, 118:-, 2021; PubMed: 33782129; DOI: 10.1073/pnas.2023839118

実験手法

X-RAY DIFFRACTION (2.8 Å)