7AUA
Cryo-EM structure of human exostosin-like 3 (EXTL3) in complex with UDP
Summary for 7AUA
Entry DOI | 10.2210/pdb7aua/pdb |
Related | 7AU2 |
EMDB information | 11923 11926 |
Descriptor | Exostosin-like 3, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | glycosyltransferase, heparan, n-acetylglucosaminyltransferase, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 206674.60 |
Authors | Wilson, L.F.L.,Dendooven, T.,Hardwick, S.W.,Chirgadze, D.Y.,Luisi, B.F.,Logan, D.T.,Mani, K.,Dupree, P. (deposition date: 2020-11-02, release date: 2022-05-18, Last modification date: 2022-06-15) |
Primary citation | Wilson, L.F.L.,Dendooven, T.,Hardwick, S.W.,Echevarria-Poza, A.,Tryfona, T.,Krogh, K.B.R.M.,Chirgadze, D.Y.,Luisi, B.F.,Logan, D.T.,Mani, K.,Dupree, P. The structure of EXTL3 helps to explain the different roles of bi-domain exostosins in heparan sulfate synthesis. Nat Commun, 13:3314-3314, 2022 Cited by PubMed: 35676258DOI: 10.1038/s41467-022-31048-2 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.93 Å) |
Structure validation
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