7AUA
Cryo-EM structure of human exostosin-like 3 (EXTL3) in complex with UDP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Exostosin-like 3 | polymer | 890 | 101705.1 | 2 | UniProt (O43909) Pfam (PF03016) Pfam (PF09258) | Homo sapiens (Human) | EXT-related protein 1,Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase,Hereditary multiple exostoses gene isolog,Multiple exostosis-like protein 3,Putative tumor suppressor protein EXTL3 |
| 2 | C, E (C, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 3 | D, F (D, F) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 2 | In PDB GlyTouCan (G81315DD) | |||
| 4 | G, I (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) PubChem (27854) | |||
| 5 | H, J (A, B) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 2 | Chemie (UDP) PubChem (1158) PubChem (6031) PubChem (25323044) PubChem (25323048) PubChem (44298965) PubChem (53486216) PubChem (60098857) PubChem (57448939) PubChem (3084486) PubChem (91746160) PubChem (6101632) PubChem (92332560) PubChem (92332561) PubChem (92332562) PubChem (92332563) PubChem (93088131) PubChem (93630083) PubChem (6604175) PubChem (11811538) PubChem (12049241) |
Sequence modifications
A, B: 51 - 919 (UniProt: O43909)
| PDB | External Database | Details |
|---|---|---|
| Ala 30 | - | expression tag |
| Pro 31 | - | expression tag |
| Gln 32 | - | expression tag |
| Leu 33 | - | expression tag |
| His 34 | - | expression tag |
| His 35 | - | expression tag |
| His 36 | - | expression tag |
| His 37 | - | expression tag |
| His 38 | - | expression tag |
| His 39 | - | expression tag |
| Asp 40 | - | expression tag |
| Leu 41 | - | expression tag |
| Tyr 42 | - | expression tag |
| Glu 43 | - | expression tag |
| Asn 44 | - | expression tag |
| Leu 45 | - | expression tag |
| Tyr 46 | - | expression tag |
| Phe 47 | - | expression tag |
| Gln 48 | - | expression tag |
| Gly 49 | - | expression tag |
| Lys 50 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 203410.2 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2346.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 918.2 | |
| All* | Total formula weight | 206674.6 |
