7AOV

Crystal Structure of a TRPM2 Domain

Summary for 7AOV

Entry DOI	10.2210/pdb7aov/pdb
Descriptor	Transient receptor potential cation channel subfamily M member 2, ZINC ION (3 entities in total)
Functional Keywords	trpm2, signaling protein
Biological source	Danio rerio (Zebrafish, Brachydanio rerio)
Total number of polymer chains	2
Total formula weight	96125.87
Authors	Sander, S.,Tidow, H. (deposition date: 2020-10-15, release date: 2022-03-02, Last modification date: 2022-08-17)
Primary citation	Sander, S.,Pick, J.,Gattkowski, E.,Fliegert, R.,Tidow, H. The crystal structure of TRPM2 MHR1/2 domain reveals a conserved Zn 2+ -binding domain essential for structural integrity and channel activity. Protein Sci., 31:e4320-e4320, 2022 Cited by PubMed: 35634784 DOI: 10.1002/pro.4320 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.00001625778 Å)

Structure validation