7AKZ

Deciphering the role of the channel constrictions in the opening mechanism of MexAB-OprM efflux pump from Pseudomonas aeruginosa

7AKZ の概要

• エントリーDOI: 10.2210/pdb7akz/pdb
• 分子名称: Outer membrane protein OprM, PALMITIC ACID, octyl beta-D-glucopyranoside (3 entities in total)
• 機能のキーワード: efflux pump, antibiotic resistance, tolc-like, channel., translocase
• 由来する生物種: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 104116.20

構造登録者

Ntsogo Enguene, V.Y.,Monlezun, L.,Ma, M.,Garnier, C.,Lascombe, M.B.,Salem, M.,Guenard, S.,Plesiat, P.,Llanes, C.,Phan, G.,Broutin, I. (登録日: 2020-10-02, 公開日: 2022-04-13, 最終更新日: 2024-01-31)

• 主引用文献: Ntsogo Enguene, V.Y.,Monlezun, L.,Ma, M.,Garnier, C.,Lascombe, M.B.,Salem, M.,Guenard, S.,Plesiat, P.,Llanes, C.,Phan, G.,Broutin, I.; Deciphering the role of the channel constrictions in the opening mechanism of MexAB-OprM efflux pump from Pseudomonas aeruginosa; To Be Published,

実験手法

X-RAY DIFFRACTION (3.2 Å)