7AGR
Structure of the M624V-S726F mutant of AcylTransferase domain of Mycocerosic Acid Synthase from Mycobacterium tuberculosis soaked with MethylMalonyl Coenzyme A
Summary for 7AGR
Entry DOI | 10.2210/pdb7agr/pdb |
Related | 7AGP 7AGQ 7AGS 7AGT 7AGU |
Descriptor | Mycocerosic acid synthase, 1,2-ETHANEDIOL (3 entities in total) |
Functional Keywords | mycocerosic acid synthase, acyltransferase domain, polyketide synthase, mycobacterium tuberculosis, transferase |
Biological source | Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) |
Total number of polymer chains | 2 |
Total formula weight | 93058.97 |
Authors | Brison, Y.,Mourey, L.,Maveyraud, L. (deposition date: 2020-09-23, release date: 2020-12-16, Last modification date: 2024-01-31) |
Primary citation | Grabowska, A.D.,Brison, Y.,Maveyraud, L.,Gavalda, S.,Faille, A.,Nahoum, V.,Bon, C.,Guilhot, C.,Pedelacq, J.D.,Chalut, C.,Mourey, L. Molecular Basis for Extender Unit Specificity of Mycobacterial Polyketide Synthases. Acs Chem.Biol., 15:3206-3216, 2020 Cited by PubMed: 33237724DOI: 10.1021/acschembio.0c00772 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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