7AGP

Structure of the AcylTransferase domain of Mycocerosic Acid Synthase from Mycobacterium tuberculosis

Summary for 7AGP

• Entry DOI: 10.2210/pdb7agp/pdb
• Related: 7AGQ 7AGR 7AGS 7AGT 7AGU
• Descriptor: Mycocerosic acid synthase, 1,2-ETHANEDIOL (3 entities in total)
• Functional Keywords: mycocerosic acid synthase, acyltransferase domain, polyketide synthase, mycobacterium tuberculosis, transferase
• Biological source: Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
• Total number of polymer chains: 2
• Total formula weight: 93064.97

Authors

Brison, Y.,Nahoum, V.,Mourey, L.,Maveyraud, L. (deposition date: 2020-09-23, release date: 2020-12-09, Last modification date: 2024-01-31)

• Primary citation: Grabowska, A.D.,Brison, Y.,Maveyraud, L.,Gavalda, S.,Faille, A.,Nahoum, V.,Bon, C.,Guilhot, C.,Pedelacq, J.D.,Chalut, C.,Mourey, L.; Molecular Basis for Extender Unit Specificity of Mycobacterial Polyketide Synthases.; Acs Chem.Biol., 15:3206-3216, 2020; PubMed: 33237724; DOI: 10.1021/acschembio.0c00772

Experimental method

X-RAY DIFFRACTION (2.4 Å)