7AEO
Human ARTD2 in complex with DNA oligonucleotides
Summary for 7AEO
Entry DOI | 10.2210/pdb7aeo/pdb |
Descriptor | Poly [ADP-ribose] polymerase 2, DNA, SULFATE ION, ... (4 entities in total) |
Functional Keywords | artd2, parp2, dna-damage, dna-repair, adp-ribosylation, dna-binding protein, dna binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 66713.29 |
Authors | Obaji, E.,Maksimainen, M.M.,Galera-Prat, A.,Lehtio, L. (deposition date: 2020-09-17, release date: 2021-05-19, Last modification date: 2024-01-31) |
Primary citation | Obaji, E.,Maksimainen, M.M.,Galera-Prat, A.,Lehtio, L. Activation of PARP2/ARTD2 by DNA damage induces conformational changes relieving enzyme autoinhibition. Nat Commun, 12:3479-3479, 2021 Cited by PubMed: 34108479DOI: 10.1038/s41467-021-23800-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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