7AAP
Nsp7-Nsp8-Nsp12 SARS-CoV2 RNA-dependent RNA polymerase in complex with template:primer dsRNA and favipiravir-RTP
Summary for 7AAP
Entry DOI | 10.2210/pdb7aap/pdb |
EMDB information | 11692 |
Descriptor | Non-structural protein 12, Non-structural protein 8, Non-structural protein 7, ... (9 entities in total) |
Functional Keywords | rna-dependent rna polymerase, favipiravir, sars-cov2, ncovid19, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More |
Total number of polymer chains | 6 |
Total formula weight | 181600.83 |
Authors | Naydenova, K.,Muir, K.W.,Wu, L.F.,Zhang, Z.,Coscia, F.,Peet, M.,Castro-Hartman, P.,Qian, P.,Sader, K.,Dent, K.,Kimanius, D.,Sutherland, J.D.,Lowe, J.,Barford, D.,Russo, C.J. (deposition date: 2020-09-04, release date: 2020-09-23, Last modification date: 2024-07-10) |
Primary citation | Naydenova, K.,Muir, K.W.,Wu, L.F.,Zhang, Z.,Coscia, F.,Peet, M.J.,Castro-Hartmann, P.,Qian, P.,Sader, K.,Dent, K.,Kimanius, D.,Sutherland, J.D.,Lowe, J.,Barford, D.,Russo, C.J. Structure of the SARS-CoV-2 RNA-dependent RNA polymerase in the presence of favipiravir-RTP. Proc.Natl.Acad.Sci.USA, 118:-, 2021 Cited by PubMed: 33526596DOI: 10.1073/pnas.2021946118 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.5 Å) |
Structure validation
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