7A77
Crystal structure of RXR alpha LBD in complexes with palmitic acid and GRIP-1 peptide
Summary for 7A77
Entry DOI | 10.2210/pdb7a77/pdb |
Descriptor | Retinoic acid receptor RXR-alpha, Nuclear receptor coactivator 2, 1,2-ETHANEDIOL, ... (6 entities in total) |
Functional Keywords | rxra, steroid hormone receptor, inhibitor, lipid binding, fatty acid, structural genomics consortium, sgc, dna binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 29357.50 |
Authors | Chaikuad, A.,Merk, D.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2020-08-27, release date: 2020-10-21, Last modification date: 2024-01-31) |
Primary citation | Chaikuad, A.,Pollinger, J.,Ruhl, M.,Ni, X.,Kilu, W.,Heering, J.,Merk, D. Comprehensive Set of Tertiary Complex Structures and Palmitic Acid Binding Provide Molecular Insights into Ligand Design for RXR Isoforms. Int J Mol Sci, 21:-, 2020 Cited by PubMed: 33187070DOI: 10.3390/ijms21228457 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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