7A74

Structure of G132N BlaC from Mycobacterium tuberculosis

Summary for 7A74

• Entry DOI: 10.2210/pdb7a74/pdb
• Descriptor: Beta-lactamase, GLYCEROL, 1,2-ETHANEDIOL, ... (6 entities in total)
• Functional Keywords: blac, beta-lactamase, mycobacterium tuberculosis, hydrolase
• Biological source: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
• Total number of polymer chains: 1
• Total formula weight: 29880.11

Authors

Chikunova, A.,Ahmad, M.U.,Perrakis, A.,Ubbink, M. (deposition date: 2020-08-27, release date: 2021-05-19, Last modification date: 2024-01-31)

• Primary citation: Elings, W.,Chikunova, A.,van Zanten, D.B.,Drenth, R.,Ahmad, M.U.D.,Blok, A.J.,Timmer, M.,Perrakis, A.,Ubbink, M.; Two beta-Lactamase Variants with Reduced Clavulanic Acid Inhibition Display Different Millisecond Dynamics.; Antimicrob.Agents Chemother., 65:e0262820-e0262820, 2021; PubMed: 34031049; DOI: 10.1128/AAC.02628-20

Experimental method

X-RAY DIFFRACTION (1.6 Å)