7A6O
Crystal Structure of the Complex of the Recombinant Von Willebrand Factor AIM-A1 domain and VHH81 at 2.1 Angstrom resolution
Summary for 7A6O
Entry DOI | 10.2210/pdb7a6o/pdb |
Descriptor | von Willebrand factor, VHH81 Nanobody fragment, SULFATE ION, ... (4 entities in total) |
Functional Keywords | thrombosis von willebrand factor a1 aim-a1 blood clotting complex vwf, blood clotting |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 37399.70 |
Authors | Brown, A.K.,Emsley, J. (deposition date: 2020-08-25, release date: 2021-03-03, Last modification date: 2024-01-31) |
Primary citation | Arce, N.A.,Cao, W.,Brown, A.K.,Legan, E.R.,Wilson, M.S.,Xu, E.R.,Berndt, M.C.,Emsley, J.,Zhang, X.F.,Li, R. Activation of von Willebrand factor via mechanical unfolding of its discontinuous autoinhibitory module. Nat Commun, 12:2360-2360, 2021 Cited by PubMed: 33883551DOI: 10.1038/s41467-021-22634-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.117 Å) |
Structure validation
Download full validation report