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7A0Y

Structure of dimeric sodium proton antiporter NhaA K300R variant, at pH 8.2, crystallized with chimeric Fab antibodies

Summary for 7A0Y
Entry DOI10.2210/pdb7a0y/pdb
DescriptorNa(+)/H(+) antiporter NhaA, chimeric antibody Fab-F6, heavy chain,chimeric antibody Fab-F6, heavy chain, chimeric antibody Fab-F6, light chain,chimeric antibody Fab-F6, light chain, ... (10 entities in total)
Functional Keywordssodium proton antiporter, transporter, membrane protein, chimeric fab, antibody
Biological sourceSalmonella enterica subsp. enterica serovar Typhimurium str. LT2
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Total number of polymer chains6
Total formula weight190539.53
Authors
Fippel, A.,Mir, S.H.,Lentes, C.J.,Wirth, C.,Hunte, C. (deposition date: 2020-08-11, release date: 2022-02-23, Last modification date: 2024-11-06)
Primary citationFippel, A.,Mir, S.H.,Wirth, C.,Gross, N.M.,Lentes, C.J.,Bialas, E.,Frank, F.,Ulbrich, M.H.,Andrade, S.L.A.,Kulik, A.,Hunte, C.
Molecular determinants for substrate uptake in electrogenic sodium/proton antiporters
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.45 Å)
Structure validation

237735

数据于2025-06-18公开中

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