7ZX2

Tubulin-Pelophen B complex

Summary for 7ZX2

Entry DOI	10.2210/pdb7zx2/pdb
Descriptor	Tubulin alpha-1B chain, GUANOSINE-5'-DIPHOSPHATE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (15 entities in total)
Functional Keywords	tubulin, pelophen, peloruside, laulimalide, cell cycle/inhibitor, cell cycle-inhibitor complex
Biological source	Rattus norvegicus (Norway rat) More
Total number of polymer chains	6
Total formula weight	271078.05
Authors	Estevez-Gallego, J.,Diaz, J.F.,Van der Eycken, J.,Oliva, M.A. (deposition date: 2022-05-20, release date: 2022-11-23, Last modification date: 2024-02-07)
Primary citation	Estevez-Gallego, J.,Alvarez-Bernad, B.,Pera, B.,Wullschleger, C.,Raes, O.,Menche, D.,Martinez, J.C.,Lucena-Agell, D.,Prota, A.E.,Bonato, F.,Bargsten, K.,Cornelus, J.,Gimenez-Abian, J.F.,Northcote, P.,Steinmetz, M.O.,Kamimura, S.,Altmann, K.H.,Paterson, I.,Gago, F.,Van der Eycken, J.,Diaz, J.F.,Oliva, M.A. Chemical modulation of microtubule structure through the laulimalide/peloruside site. Structure, 31:88-99.e5, 2023 Cited by PubMed: 36462501 DOI: 10.1016/j.str.2022.11.006 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation