7ZSD
cryo-EM structure of omicron spike in complex with de novo designed binder, local
Summary for 7ZSD
Entry DOI | 10.2210/pdb7zsd/pdb |
EMDB information | 14922 14930 |
Descriptor | Spike glycoprotein, de novo designed binder, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | sars-cov2, de novo, design binder, spike, rbd, receptor binding domain, antiviral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 More |
Total number of polymer chains | 2 |
Total formula weight | 31534.50 |
Authors | Pablo, G.,Sarah, W.,Alexandra, V.H.,Anthony, M.,Andreas, S.,Zander, H.,Dongchun, N.,Shuguang, T.,Freyr, S.,Casper, G.,Priscilla, T.,Alexandra, T.,Stephane, R.,Sandrine, G.,Jane, M.,Aaron, P.,Zepeng, X.,Yan, C.,Pu, H.,George, G.,Elisa, O.,Beat, F.,Didier, T.,Henning, S.,Michael, B.,Bruno, E.C. (deposition date: 2022-05-06, release date: 2023-03-01, Last modification date: 2023-05-24) |
Primary citation | Gainza, P.,Wehrle, S.,Van Hall-Beauvais, A.,Marchand, A.,Scheck, A.,Harteveld, Z.,Buckley, S.,Ni, D.,Tan, S.,Sverrisson, F.,Goverde, C.,Turelli, P.,Raclot, C.,Teslenko, A.,Pacesa, M.,Rosset, S.,Georgeon, S.,Marsden, J.,Petruzzella, A.,Liu, K.,Xu, Z.,Chai, Y.,Han, P.,Gao, G.F.,Oricchio, E.,Fierz, B.,Trono, D.,Stahlberg, H.,Bronstein, M.,Correia, B.E. De novo design of protein interactions with learned surface fingerprints. Nature, 617:176-184, 2023 Cited by PubMed: 37100904DOI: 10.1038/s41586-023-05993-x PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.29 Å) |
Structure validation
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