7ZR2

Crystal structure of a chimeric protein mimic of SARS-CoV-2 Spike HR1 in complex with HR2

Summary for 7ZR2

Entry DOI	10.2210/pdb7zr2/pdb
Descriptor	Spike protein S2',Chimeric protein mimic of SARS-CoV-2 Spike HR1, Spike protein S2' (3 entities in total)
Functional Keywords	coiled-coil, antiviral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 More
Total number of polymer chains	2
Total formula weight	31250.85
Authors	Camara-Artigas, A.,Gavira, J.A.,Cano-Munoz, M.,Polo-Megias, D.,Conejero-Lara, F. (deposition date: 2022-05-03, release date: 2022-11-09, Last modification date: 2024-01-31)
Primary citation	Cano-Munoz, M.,Polo-Megias, D.,Camara-Artigas, A.,Gavira, J.A.,Lopez-Rodriguez, M.J.,Laumond, G.,Schmidt, S.,Demiselle, J.,Bahram, S.,Moog, C.,Conejero-Lara, F. Novel chimeric proteins mimicking SARS-CoV-2 spike epitopes with broad inhibitory activity. Int.J.Biol.Macromol., 222:2467-2478, 2022 Cited by PubMed: 36220405 DOI: 10.1016/j.ijbiomac.2022.10.031 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.45 Å)

Structure validation