7ZR2
Crystal structure of a chimeric protein mimic of SARS-CoV-2 Spike HR1 in complex with HR2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Spike protein S2',Chimeric protein mimic of SARS-CoV-2 Spike HR1 | polymer | 241 | 26577.7 | 1 | UniProt (P0DTC2) Pfam (PF01601) In PDB | Severe acute respiratory syndrome coronavirus 2 | |
2 | B | Spike protein S2' | polymer | 44 | 4673.1 | 1 | UniProt (P0DTC2) In PDB | Severe acute respiratory syndrome coronavirus 2 | |
3 | water | water | 18.0 | 304 | Chemie (HOH) |
Sequence modifications
A: 1 - 73 (UniProt: P0DTC2)
A: 73 - 154 (PDB: 7ZR2)
A: 155 - 229 (UniProt: P0DTC2)
B: 1163 - 1206 (UniProt: P0DTC2)
PDB | External Database | Details |
---|---|---|
Met 0 | - | initiating methionine |
Asp 1 | Asn 914 | engineered mutation |
Lys 13 | Gln 926 | engineered mutation |
Glu 31 | Ala 944 | engineered mutation |
Glu 38 | Val 951 | engineered mutation |
Asp 45 | Ala 958 | engineered mutation |
Arg 59 | Ala 972 | engineered mutation |
Glu 63 | Val 976 | engineered mutation |
A: 155 - 229 (UniProt: P0DTC2)
PDB | External Database | Details |
---|---|---|
Glu 165 | Ala 924 | engineered mutation |
Lys 183 | Ala 942 | engineered mutation |
Lys 190 | Gln 949 | engineered mutation |
Lys 197 | Ala 956 | engineered mutation |
Lys 222 | Leu 981 | engineered mutation |
Gly 230 | - | expression tag |
Gly 231 | - | expression tag |
Gly 232 | - | expression tag |
Gly 233 | - | expression tag |
Ser 234 | - | expression tag |
His 235 | - | expression tag |
His 236 | - | expression tag |
His 237 | - | expression tag |
His 238 | - | expression tag |
His 239 | - | expression tag |
His 240 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ace 1163 | Asp 1163 | conflict |
Ser 1203 | Leu 1203 | conflict |
Gly 1205 | Lys 1205 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 31250.8 | |
All* | Total formula weight | 31250.8 |