7ZL1
PTX3 Pentraxin Domain
Summary for 7ZL1
Entry DOI | 10.2210/pdb7zl1/pdb |
EMDB information | 14774 |
Descriptor | Pentraxin-related protein PTX3, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | ptx3, long pentraxin 3, immune system, innate immunity |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 8 |
Total formula weight | 336512.98 |
Authors | Noone, D.P.,Sharp, T.H. (deposition date: 2022-04-13, release date: 2022-08-03, Last modification date: 2022-08-17) |
Primary citation | Noone, D.P.,Dijkstra, D.J.,van der Klugt, T.T.,van Veelen, P.A.,de Ru, A.H.,Hensbergen, P.J.,Trouw, L.A.,Sharp, T.H. PTX3 structure determination using a hybrid cryoelectron microscopy and AlphaFold approach offers insights into ligand binding and complement activation. Proc.Natl.Acad.Sci.USA, 119:e2208144119-e2208144119, 2022 Cited by PubMed: 35939690DOI: 10.1073/pnas.2208144119 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.5 Å) |
Structure validation
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