7Z8U
Catalytic subunit HisG R56A mutant from Psychrobacter arcticus ATPPRT (HisGZ) in complex with ATP and PRPP
Summary for 7Z8U
Entry DOI | 10.2210/pdb7z8u/pdb |
Descriptor | ATP phosphoribosyltransferase, 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, ADENOSINE-5'-TRIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | atp, phosphoribosyltransferase, atpprt, prpp, hisg, hisgz, histidine, biosynthesis, allosteric, transferase |
Biological source | Psychrobacter arcticus |
Total number of polymer chains | 1 |
Total formula weight | 26076.41 |
Authors | Alphey, M.S.,Fisher, G.,da Silva, R.G. (deposition date: 2022-03-18, release date: 2022-03-30, Last modification date: 2024-02-07) |
Primary citation | Fisher, G.,Corbella, M.,Alphey, M.S.,Nicholson, J.,Read, B.J.,Kamerlin, S.C.L.,da Silva, R.G. Allosteric rescue of catalytically impaired ATP phosphoribosyltransferase variants links protein dynamics to active-site electrostatic preorganisation. Nat Commun, 13:7607-7607, 2022 Cited by PubMed: 36494361DOI: 10.1038/s41467-022-34960-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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