7YP8
Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with Leucyl-sulfamoyl 3-deazaadenosine
Summary for 7YP8
Entry DOI | 10.2210/pdb7yp8/pdb |
Descriptor | Leucine--tRNA ligase, 1,2-ETHANEDIOL, [(2R,3S,4R,5R)-5-(4-azanylimidazo[4,5-c]pyridin-1-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl N-[(2S)-2-azanyl-4-methyl-pentanoyl]sulfamate, ... (6 entities in total) |
Functional Keywords | protein-inhibitor complex, rossmann fold, trna synthetase, ligase |
Biological source | Neisseria gonorrhoeae (strain NCCP11945) |
Total number of polymer chains | 1 |
Total formula weight | 98795.61 |
Authors | Pang, L.,De Graef, S.,Strelkov, S.V.,Weeks, S.D. (deposition date: 2022-08-02, release date: 2024-02-07) |
Primary citation | Pang, L.,De Graef, S.,Zhang, B.,Strelkov, S.V.,Van Aerschot, A.,Weeks, S.D. The essential role of a structured water in base recognition of Class II aminoacyl-tRNA synthetases To be published, |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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