7YOW

Crystal structure of SARS-CoV-2 omicron variant spike receptor-binding domain (RBD) in complex with NCV2SG48 Fab

Summary for 7YOW

• Entry DOI: 10.2210/pdb7yow/pdb
• Related: 7WN2 7WNB
• Descriptor: Fab Light chain, Fab Heavy chain, Spike protein S1, ... (4 entities in total)
• Functional Keywords: spike, coronavirus omicron strain, viral protein, fab, viral protein-immune system complex, virus, immune system-viral protein complex, immune system/viral protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 6
• Total formula weight: 148037.49

Authors

Yamamoto, A.,Higashiura, A. (deposition date: 2022-08-02, release date: 2023-04-19, Last modification date: 2023-11-29)

• Primary citation: Shitaoka, K.,Higashiura, A.,Kawano, Y.,Yamamoto, A.,Mizoguchi, Y.,Hashiguchi, T.,Nishimichi, N.,Huang, S.,Ito, A.,Ohki, S.,Kanda, M.,Taniguchi, T.,Yoshizato, R.,Azuma, H.,Kitajima, Y.,Yokosaki, Y.,Okada, S.,Sakaguchi, T.,Yasuda, T.; Structural basis of spike RBM-specific human antibodies counteracting broad SARS-CoV-2 variants.; Commun Biol, 6:395-395, 2023; PubMed: 37041231; DOI: 10.1038/s42003-023-04782-6

Experimental method

X-RAY DIFFRACTION (3.3 Å)