7Y8D
Crystal structure of cp1 bound BCLxl
Summary for 7Y8D
Entry DOI | 10.2210/pdb7y8d/pdb |
Descriptor | Bcl-2-like protein 1, cp1 peptide, (2R)-3-[2-(aminomethyl)-3-azanyl-1-[4-[2-(2-chloranylethanoylamino)ethylcarbamoyl]phenyl]prop-1-enyl]sulfanyl-2-(carboxyamino)propanoic acid, ... (4 entities in total) |
Functional Keywords | anti-apoptosis protein, apoptosis |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 18087.65 |
Authors | |
Primary citation | Li, F.,Liu, J.,Liu, C.,Liu, Z.,Peng, X.,Huang, Y.,Chen, X.,Sun, X.,Wang, S.,Chen, W.,Xiong, D.,Diao, X.,Wang, S.,Zhuang, J.,Wu, C.,Wu, D. Cyclic peptides discriminate BCL-2 and its clinical mutants from BCL-X L by engaging a single-residue discrepancy. Nat Commun, 15:1476-1476, 2024 Cited by PubMed: 38368459DOI: 10.1038/s41467-024-45848-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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