7Y42

Cryo-EM structure of the SARS-CoV-2 spike glycoprotein in complex with all-trans retinoic acid

Summary for 7Y42

• Entry DOI: 10.2210/pdb7y42/pdb
• EMDB information: 33600
• Descriptor: Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose, RETINOIC ACID (3 entities in total)
• Functional Keywords: viral protein-inhibitor complex, viral protein/inhibitor
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 3
• Total formula weight: 379379.44

Authors

Xiang, Y.,Wang, L. (deposition date: 2022-06-13, release date: 2022-07-06, Last modification date: 2022-09-14)

• Primary citation: Tong, L.,Wang, L.,Liao, S.,Xiao, X.,Qu, J.,Wu, C.,Zhu, Y.,Tai, W.,Huang, Y.,Wang, P.,Li, L.,Zhang, R.,Xiang, Y.,Cheng, G.; A Retinol Derivative Inhibits SARS-CoV-2 Infection by Interrupting Spike-Mediated Cellular Entry.; Mbio, 13:e0148522-e0148522, 2022; PubMed: 35862773; DOI: 10.1128/mbio.01485-22

Experimental method

ELECTRON MICROSCOPY (3.45 Å)